LRP1 and Alzheimer disease: The combined analysis showed that there was no significant association between LRP1 C766T polymorphism and AD susceptibility in any genetic model (T versus C: OR = 0.905, 95% CI = 0.813–1.008, P = 0.069; TT versus CC: OR = 0.791, 95% CI = 0.622–1.005, P = 0.055; CT versus CC: OR = 0.915, 95% CI = 0.813–1.030, P = 0.139; TT + CT versus CC: OR = 0.920, 95% CI = 0.817–1.037, P = 0.172; TT versus CC + CT: OR = 0.815, 95% CI = 0.640–1.037, P = 0.095) (Table 3 and Fig. 2).