Non-tau pathology reported in nfaPPA include frontotemporal lobar degeneration-ubiquitin positive inclusions (FTLD-U) [26–27], Alzheimer’s disease (AD) pathology [28–30], frontotemporal lobar-TAR DNA binding protein (FTLD-TDP) [31–33], and TAR DNA binding protein 43(FTLD-TDP-43) [33]. Here, TARDBP is linked to Alzheimer disease.