In multiple cancers such as non-small cell lung carcinoma, hepatocellular carcinoma, lung cancer, cervical cancer, pancreatic carcinoma as well as ccRCC, MALAT1 is overexpressed and acts as an oncogene [35,205,206] by enhancing cell growth, tumorigenesis and metastasis through modulation of ERK/MAPK pathway [35,207]. This evidence concerns the gene MALAT1 and nonpapillary renal cell carcinoma.