TP53 and hepatocellular carcinoma: To further explore the expression changes of identified miRNAs in oxidative stress response in HCC, we treated four TP53 wild-type HCC cell lines with 200 μM H2O2 (the most widely used concertation) for 24 h and measured expression levels of four miRNAs (miR-34a-5p, miR-1915-3p, miR-638, and miR-150-3p).