The expression was more common in Papillary carcinoma as compared to follicular carcinoma because out of 21/28 PC (75%) showed positive reaction and only 7/28 (25%) showed a negative reaction while only 3/9 (33%) follicular carcinoma showed positive staining for Galectin-3 antibody and 6/9 (67%) remained negative (Table II-III and Fig.2). This evidence concerns the gene LGALS3 and pachyonychia congenita.