INS and type 1 diabetes mellitus: Acarbose inhibits digestion into monosaccharides and offsetting post-prandial glucose rise while metformin inhibits hepatic glucose production and improves peripheral insulin sensitivity.2,12,15,16 The effectiveness of acarbose and metformin in patients with T1DM has been evaluated in previous studies separately but studies that focus on comparing the effect of these two drugs are limited.