Furthermore, the serum cytokine profiles of CTS patients were readily distinguishable from those of controls with distinct patterns of the chemokines CCL2, CCL4, CCL5, CXCL8 and CXCL10 and the growth factors VEGF, PDGF and G-CSF, which may be induced by the neuropathy. This evidence concerns the gene CCL5 and carpal tunnel syndrome.