INS and type 1 diabetes mellitus: Plasma insulin level in T1DM patients was 1.5 μU of insulin/mL (median ranging from 0.02 μU of insulin/mL to 2.2 μU of insulin/mL) and plasma insulin level in normal subject was 14 μU of insulin/mL (median ranging from 7 μU of insulin/mL to 13.7 μU of insulin/mL) (Fig. 2E).