TNF and neoplasm: However, there was a significant effect of tumor cell type on IL-1β (Fig. 1C, H = 29.44, p < 0.0001), IL-6 (Fig. 1C, F2,37 = 13.68, p < 0.0001), TNFα (Fig. 1C, F2,38 = 26.73, p < 0.0001), and CXCL1 (Fig. 1C, H = 10.86, p < 0.005).