SOX4 and hepatocellular carcinoma: After 48 h transfection, we found that HOXD-AS1 was enriched to more than fourfold in Bi-miR-130a-3p pull down of HCC cells as compared to Bi-cel-miR67 transfection, and also we observed more than fivefold enrichment of SOX4 in the miR-130a-3p captured fraction compared with the negative control (Fig. 5e).