Interestingly, in principle, the patient was referred as having “genotype-negative” LQTS since no mutations were identified in any of the major LQTS-related genes (SCN5A, KCNH2, KCNQ1, KCNE1, KCNE2, and KCNJ2) [33]. This evidence concerns the gene KCNE2 and familial long QT syndrome.