The total prostate specific antigen (TPSA) was 26.31 ± 8.19 ng/ml (range, 1.76~36.12 ng/ml) and 1.75 ± 0.24 ng/ml (0.00~3.19 ng/ml) in benign prostate hyperplasia group. This evidence concerns the gene KLK3 and benign prostatic hyperplasia.