TNFRSF18 and neoplasm: While anti-GITR Ab (aGITR) alone did not show any therapeutic benefit, its addition to Lm-LLO-E7 led to further significant enhancement of treatment efficacy, resulting in even more profound inhibition of tumor growth (****P ≤ 0.0001) (Fig. 1b-c) and complete regression of tumors in 60% of animals (****P ≤ 0.0001) (Fig. 1d-e).