As with squamous cell carcinoma, risk associations were seen between adenocarcinoma and HLA Class I (HLA-B*0702 (OR = 1.48, P = 2.65 × 10−5)) and Class II (HLA-DRB1*15 (OR = 1.49, P = 0.00012; HLA-DQB1*0602 (OR = 1.48, P = 0.00026) alleles. The gene discussed is HLA-DQB1; the disease is adenocarcinoma.