For squamous cell carcinoma, the strongest risk HLA allele associations were seen with HLA-DQB1*0602 (OR = 1.52, P = 1.47 × 10−7) and HLA-DRB1*1501 (OR = 1.50, P = 2.95 × 10−7). This evidence concerns the gene HLA-DQB1 and squamous cell carcinoma.