The HLA-DRB1*1301/HLA-DQA1*0103/HLA-DQB1*0603 haplotype has previously been associated with protection from oral and oropharyngeal cancer, particularly in HPV-positive cases (OR = 0.23, P = 1.6 × 10−6) [28]. The gene discussed is HLA-DRB1; the disease is oropharynx cancer.