LMNA and carcinoma: Lamins are divided into A-type and B-type, which are encoded by three genes, LMNA, LMNB1, and LMNB2. The alternative splicing of LMNA, located at chromosome 1q21.1–21.3, produces two major A-type lamins, lamin A and lamin C, which are expressed in most differentiated cells, and two minor isoforms, lamin AΔ10, which is expressed in some carcinoma cell lines [12], and lamin C2, which is specifically expressed in germ cells.