Quantification over time showed that 70% of Mav resided in LAMP1+ late endosomes/phagolysosomes as early as 15 minutes post infection, increasing to more than 90% 4 hours to 1 day post infection, suggesting Mav phagosomes are not arrested at an early endosomal stage but mature normally to a late endosomal/lysosomal stage (Fig 1G, P <0.005 for both time points). The gene discussed is LAMP1; the disease is infection.