Initially, the now famous genetic association of the dopamine D2–receptor gene (DRD2) A1 allele (variant) with severe alcoholism, was met with worldwide controversy [39] Genetic</keyword><keyword>*Polymorphism, Restriction Fragment Length</keyword><keyword>Receptors, Dopamine/*genetics</keyword><keyword>Receptors, Dopamine D2</keyword></keywords><dates><year>1992</year><pub-dates><date>Feb 1</date></pub-dates></dates> <isbn>0006-3223 (Print. This evidence concerns the gene DRD2 and alcohol dependence.