FN1 and liver dysplastic nodule: Several extracellular (ECM) proteins (e.g., collagen IV, fibronectin, laminin, and nidogen-1) and modulators of inflammation (e.g., IL-1β, IL-6, IL-18, and MCP-1) are proteolytically processed by meprins, suggesting that meprins could impact inflammation and the fibrosis observed in DN.