BRCA2 and breast neoplasm: Studies have been conducted on a possible relationship between PUFAs metabolism and the pathways involving the Breast Related Cancer Antigens (BRCA) 1 and BRCA2 genes (Bernard-Gallon et al., 2002), which are implicated in inherited predisposition to BC, showing the presence of a possible transcriptional or post-transcriptional regulation of BRCA1 and BRCA2 after omega-3 PUFAs treatment in breast tumor cells (Bernard-Gallon et al., 2002; Shiovitz and Korde, 2015).