BRCA2 and breast cancer: Moreover, Bernard-Gallon et al. observed an increase of BRCA1 and BRCA2 mRNA expressions in DHA-treated BC cell lines, suggesting the presence of a possible transcriptional or post-transcriptional regulation of BRCA1 and BRCA2 genes after omega-3 PUFAs treatment in BC cells (Bernard-Gallon et al., 2002).