Among the other ERF metabolites, our results on two (1,5-AG and glycerol) are inconsistent with the previous studies in terms of direction of association: Suhre et al. studied on 40 diabetes cases and 60 healthy male controls in the German population (Suhre et al. 2010); Lu J. et al.’s study included 22 Chinese cases and 22 healthy controls (Lu et al. 2012), and the study by Shaham O. et al. was done in 47 healthy academic students (Shaham et al. 2008). This evidence concerns the gene ERF and diabetes mellitus.