LMNB1 and B-cell chronic lymphocytic leukemia: Next, when performing gene set enrichment analysis for CLL cases dichotomised for lower and upper quartiles of LMNB1 expression, we found ‘LMNB1 quartile low’ cases to extensively match signatures of anti-IgM-activated B cells (Supplementary Figure 8B) while there was only a 1.12-fold expression change for AID observable for ‘LMNB1 quartile low’ expressing CLLs (data not shown).