LMNB1 and B-cell chronic lymphocytic leukemia: Moreover, univariate Cox regression analysis comparing low (⩽ 6.51) and high (> 6.51) LMNB1 expression cohorts revealed an overall hazard ratio of 0.715 for PFS and 0.551 for OS (95% confidence interval) (Figure 3f), suggesting a strong protective impact of LMNB1 expression in CLL.