TTR and autosomal dominant disease: Hereditary transthyretin amyloidosis (ATTR amyloidosis), Online Mendelian Inheritance in Man (OMIM) 105210, is an autosomal dominant inherited disorder, first described in families from Northern Portugal with sensorimotor and autonomic neuropathy, and associated with the Val30Met (p.Val50Met) transthyretin (TTR) mutation [1].