CD4 and acute lymphoblastic leukemia: In order to identify miRNAs with putative oncogenic potential in specific T-ALL subgroups, we also performed differential expression analysis between immature T-ALLs and CD34+ thymocytes, and between TAL-R T-ALLs and CD4+CD8+ thymocytes, as these thymocyte subsets represent the stage of differentiation arrest during T cell development leading to these specific T-ALLs (Supplementary Tables S3 and S4).