PPARGC1A and essential thrombocythemia: They are rs10937625 in serine/threonine kinase STK32B, rs17590046 in the transcriptional coactivator PPARGC1A and rs12764057, rs10822974 and rs7903491 in the cell-adhesion molecule CTNNA3. Notably, the variant rs17590046 in PPARGC1A was replicated in an cohort of Asian population from Singapore16, which indicated that rs17590046 may be a common genetic factor for ET patients from Asian and European populations.