TNF and infection: We infected human (THP-1) or mice macrophages (MHS) at MOI 1:1 for 1 h with either the wild type H37Rv, the Δpmt mutant, and the Rv1002c-complemented strain and assayed inflammatory (TNF-α) or anti-inflammatory (IL-10) cytokines at 5, 24 and 48 h post-infection.