SACK1H and heart failure: We thus evaluated the relative expression of the major Gα subunits from all G protein families (Gi/o: αi1, αi2, αi3, αo - Gs: αsL - Gq/11: αq, α11, α14, α15 - G12/13: α12, α13) in cardiomyocytes isolated from mice with heart failure secondary to an experimental barometric stress induced by transverse aortic constriction previously described28.