All anti-Hp(+) MS, HCs, PD and ALZ patients were tested for antibody reactivity to individual p120-CagA, p95-VacA (by line immunoassay), p75, p67-FSH, p66-UreB, p54-flagellin, p50, p41, p33, p30-OMP, p29-UreA, p26, p19-OMP, p17 antigens (by Western immunoblot). The gene discussed is S100A8; the disease is Parkinson disease.