Bonferroni’s post hoc tests showed significant differences, with P < 0.01 for PND3, P < 0.0001 for PND4 and PND5, and P < 0.001 for PND6 (Fig. 2b), suggesting that RAGE deletion elicited a developmental delay of 11–19% in body weight during PND3–6. The gene discussed is AGER; the disease is Global developmental delay.