Although IGF‐1 was first discovered due to the observation that it was able to stimulate longitudinal growth, the list of physiological and pathophysiological processes involving this growth factor is now extensive and includes metabolism, development of specific neurosensory systems, neuroprotection, longevity, cancer, obesity, eating disorders, and neurodegenerative diseases (Argente et al, 1997a,b; Katic & Kahn, 2005; Yakar et al, 2005; Torres‐Aleman, 2012). The gene discussed is IGF1; the disease is neurodegenerative disease.