In addition, more activated CD68+ microglia were detected in the ischemia (5.1±0.7 cells/mm; p<0.001) and the ranibizumab groups (7.7±1.1 cells/mm; p<0.001) when compared to the control group (0.3±0.1 cells/mm; Fig 8D). Here, CD68 is linked to ischemia.