LGALS3 and cancer: Then, we evaluated the pooled rate of preoperative Gal-3 positivity between cancers (i.e., Gal-3 sensitivity for thyroid malignancy at FNAC): the sensitivity of Gal-3 was 90% (95% CI from 85% to 94%), ranging from 80% to 94%; the series of cancers was not heterogeneous (I2 0%, 95% CI from 0% to 67.9%) and showed no significant publication bias (Egger test: −0.87 (95% CI from −4.29 to 2.55, p = 0.389).