Therefore, the aim of this study was to explore whether severe preeclampsia is associated with changed maternal serum matrix metalloproteinases MMP-2, MMP-3, MMP-9, and MMP-13 levels (see Figures 1, 2, 3, and 4) and whether there are differences in these metalloproteinases levels in women with early- and late-onset preeclampsia. The gene discussed is MMP2; the disease is preeclampsia.