INS and type 2 diabetes mellitus: Type II diabetes is the most diffused form of diabetes (Moller, 2001; Stumvoll et al., 2005; Daneman, 2006; Nanji and Shapiro, 2006), characterized by disorders of insulin action, due to insulin resistance, and abnormalities in insulin secretion by β cells (Assal and Groop, 1999; Stumvoll et al., 2005).