RBFOX3 and ischemia: Surprisingly, in the present study, we found that the number of NeuN positive neurons is reduced not only in the CA1 area, but also in the CA3 areas at 2 weeks and 4 weeks after BCCAO, suggesting that the neurodegenerative mechanisms induced by acute transient global ischemia and CCH are distinct, and further studies are obviously important in order to appropriately use these ischemic models and to identify specific and effective therapeutic agents for treating different types of ischemia.