Furthermore, a recurrent mutation in MYH8 gene associates with trismus-pseudocamptodactyly syndrome (TPS) involving joint contracture and the inability of patients to open the mouth fully (also Dutch-Kentucky or Hecht-Beal syndrome; e.g., Toydemir et al., 2006). This evidence concerns the gene MYH8 and Trismus - pseudocamptodactyly.