Moreover, reported communication deficits in at least some cases of AD, PD, HD, LBD, ALS, ASD, SCZD, and Down syndrome (Murray, 2000; Yoder and Warren, 2004; Stephane et al., 2007; Abrahams and Geschwind, 2010; Kupferberg, 2010; Reilly et al., 2010; Ferris and Farlow, 2013) confirm the well-established involvement of FOXP2 in the evolutionary and developmental acquisition of speech and language (see, e.g., Vernes and Fisher, 2009; Bolhuis et al., 2010; Enard, 2011; but see Mallick et al., 2016). Here, FOXP2 is linked to Down syndrome.