This result suggests that Epi-5 and ATA3 might interact with a putative target molecule (receptor) via position-specific hydrogen bonds for regulating anti-cancer activities, as different mechanism from EGCG such as suppressing cell proliferation and cell invasion of PC-3 prostate cancer cells, while Cat-5 is not capable of such activity. The gene discussed is SLC38A4; the disease is Familial prostate cancer.