A reduction in CD133 positive cells was observed in tumor tissues derived from mice in the PDMP + RT group (4.25 ± 3.27) when compared with mice in the PTX + DDP(IT)+RT group (27.5 ± 4.76%, p < .05), RT group (52.25 ± 5.25%, p < .05), and other groups (p < .05 in all cases). This evidence concerns the gene PROM1 and neoplasm.