To test whether animals inoculated with dgPMCAb-derived PrPres might develop α-synucleinopathy due to possible amplification of α-synuclein aggregates in dgPMCAb, the animal group injected with dgPMCAb-derived PrPres seeded with fibrillary WT α-synuclein and un-inoculated age-matched control group were also examined by staining with anti-α-synuclein antibodies. The gene discussed is SNCA; the disease is synucleinopathy.