For example, Eto et al.[19] and Geng et al.[20] reported that when the percentage of PD-L1positivecancer cells was greater than 50%, which was the definition of PD-L1 positive, while, Kawazoe et al.[23] and Boger et al.[16] considered that PD-L1-positive cases on tumor cells were defined by the presence of at least 1% of tumor cells with membrane staining. The gene discussed is CD274; the disease is neoplasm.