CXCL1 (C-X-C motif ligand 1) has been shown to be upregulated by TLR/MyD88 activation and is important in corneal wound healing and infection [18,41–43] Therefore, we examined the baseline expression of this chemokine in untreated mice deficient in MyD88 or IL-1R. Here, CXCL1 is linked to infection.