CRNDE and colorectal carcinoma: It may function as a competing endogenous RNA to promote CRC metastasis and oxaliplatin resistance by sponging miR-136,25 or via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling promotes colorectal cancer cell proliferation and chemoresistance.24 However, the above studies have singly pointed that CRNDE plays an oncogene function by regulating miRNA.