TP53 and lung adenocarcinoma: To determine the role of endogenous mutant p53-R273H in cell mobility, we used human lung adenocarcinoma H1975 and human triple negative breast adenocarcinoma MDA-MB-468 cells, both of which express endogenous p53-R273H, and the protein levels of endogenous mutant p53-R273H are compared to the ectopic expression p53-R273H in H1299 (Supplementary Figure S1D).