KLF10 and cancer: KLF10, originally called TGF-β inducible gene 1 (TIEG1), has been found to be downregulated in human cancers and inhibits growth, radio-sensitivity and metastasis of cancer cells.25, 26, 27, 28 Here, we confirmed that KLF10 was a direct downstream target of miR-410 based on the following reasons: firstly, luciferase activity assays indicated that miR-410 could bind with the 3′-UTR of KLF10.