As shown in Fig. 3G, the proportion of CD4+CD25+FOXP3+ Treg cells was significantly higher in the HCC groups of patients with various tumor sizes than in the control group; moreover, the proportion of CD4+CD25+FOXP3+ Treg cells was significantly higher in the HCC group with a large tumor size than in the HCC group with a small tumor size. Here, CD4 is linked to neoplasm.