CEACAM5 and neoplasm: N3 stage GC has been recognized as an advanced malignancy with a poor prognosis, even after radical resection.[10] The prognosis of GC patients vary greatly even within patients at the same TNM stage.[11] Our study showed that early CEA or CA19-9 normalization after radical gastrectomy was a prognostic factor for N3 stage GC, which was particularly relevant for patients with high preoperative levels of tumor markers.