Also, while the phosphate level decreased by 0.05 (p = 0.001) and 0.04 (p < 0.001) mmol/L per year in both CKD and CKD-T patients, Klotho and albumin-adjusted calcium levels only decreased in CKD-T patients, by 0.05 log pg/mL (p = 0.03) and 0.01 mmol/L (p = 0.008) per year, respectively. The gene discussed is KL; the disease is chronic kidney disease.