Therefore, individuals with acute and chronic illness and a concomitant significant elevation in CRP levels (raised CRP levels multiples higher than baseline associated with conditions such as common cold, skin infections, urinary tract infections, joint inflammation, active autoimmune conditions such as Crohn’s disease, conditions with arterial inflammation such as polymyalgia rheumatism and malignancy) were excluded from the study. This evidence concerns the gene CRP and Arthritis.