BARD1 and neoplasm: High tumor expression of BARD1 (P = 0.002), median tumor size >5 cm (P < 0.001), multiple tumor numbers (P < 0.001), TNM stage III–IV (P < 0.001), higher BCLC stage (P < 0.001), and increased serum AST levels (P < 0.001) were identified as parameters significantly associated with PFS of HCC patients (Table 2).