Among this cohort, LUM gene expression correlates with survival in patients with melanoma, with a 4-fold increase in median overall survival being observed in the high lumican-expressing group, as determined using the optimal cut-off (calculated using the R2 web tool) of LUM mRNA expression (Bhardwaj dataset, GEO accession number GSE19234, Fig. 1d). Here, LUM is linked to melanoma.