Long intergenic noncoding RNA for kinase activation mediates heparin-binding epidermal growth factor-like growth factor-triggered, epidermal growth factor receptor: glycoprotein nonmetastatic melanoma protein B heterodimer-dependent HIF-1α phosphorylation leading to HIF-1α stabilization, HIF-1α-p300 interaction, and activation of hypoxic programs, including glycolysis under normal oxygen conditions in breast cancer (68). Here, HIF1A is linked to breast cancer.